GreenMark Receives NIH Funding for Regenerative Dental Treatment

GreenMark has announced that it’s received $200,000 in additional funding from the Michigan-Pittsburgh-Wyss Regenerative Medicine (MPWRM) program through the National Institutes of Health (NIH). This program, specifically created to develop regenerative medical and dental treatments, will provide support toward GreenMark as they develop approaches for the prevention of dental decay through mineralization.

Products such as CrystLCare™ from GreenMark and Dentulu aim to regenerate permanently, according to GreenMark CEO Steven Bloembergen, PhD.

“Rather than using sensitivity products that provide short-term relief, or common toothpastes that contain tiny ‘rocks’ of non-reactive, pre-formed crystals, this award is supporting the developing of CrystLCare Biorestorative products designed to deliver active mineral components to regenerate and restore.” Dr Bloembergen said in a press release from the company.

Sub-micron particles are directed to sites to break down natural salivary enzymes. In doing this, calcium and phosphate are released to “occlude porosities and dentinal tubules with in-situ generated apatite crystals,” per VP Technology for GreenMark and co-principal investigator of the award, Nathan Jones, MSc, PhD.

Not only does CrystLCare combat sensitivity, but it is also said to restore early-stage caries lesions, per the press release. GreenMark aims to address hypersensitivity, which is said to affect up to 74% of Americans as cited in the press release, according to Chief Dental Officer Arash Hakhamian, DDS.

“Our research shows promising signs that this innovative approach at mineralization of dentin and enamel will provide both patients and dentists new pathways for reducing sensitivity and caries,” Dr Hakhamian said in the press release. “Dentinal hypersensitivity can now be quickly and effectively addressed with our dissolvable sensitivity strips, including before and after procedures for teeth whitening and even porcelain veneers.”

CrystLCare is a biorestorative, fluoride-free product available now. To learn more about it, or GreenMark’s other products, visit the website here.